Abstract
181
Karmali, R.A.; Horrobin, D.F.; Ghayur, T.; Manku, M.S.; Cunnane, S.C.; Morgan, R.O.; Ally, A.I.; Karmazyn, M.; Oka, M.
Influence of agents which modulate thromboxane A2 synthesis or action on R3230AC mammary carcinoma
Cancer Lett 1978; 5(4): 205-8.


Abstract

The effects of agents which modulate thromboxane A2 synthesis or action, were tested in the R3230AC transplanted mammary tumour. Three different inhibitors of thromboxane A2 synthesis or action (copper, dipyridamole and diazepam) all caused an increase in tumour growth. Colchicine and melatonin, both stimulators of thromboxane A2 synthesis, inhibited the growth of the tumour significantly.


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© Peter Lapinskas 1999-2012 Email Peter Lapinskas Last updated: 3 July 2012

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