Horrobin, D.F.; Manku, M.S.; Huang, Y.S.
Effects of essential fatty acids on prostaglandin biosynthesis
Biomed Biochim Acta 1984; 43(8-9): S114-20.


Prostaglandins (PGs) are derived from dietary essential fatty acids (EFAs) by relatively short biochemical pathways. PG synthesis can be manipulated by modifying EFA intake. PGs and related compounds of the 1 and 3 series have desirable or neutral actions while those of the 2 series are mixed, some being desirable but others being highly undesirable. Methods for selectively increasing 1 and 3 series products while simultaneously reducing the formation of arachidonic acid derivatives are described.

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